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Weighted Graph Comparison Techniques for Brain Connectivity Analysis

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The analysis of brain connectivity is a vast field in neuroscience with a frequent use of visual representations and an increasing need for visual analysis tools. Based on an in-depth literature review and interviews with neuroscientists, we explore high-level brain connectivity analysis tasks that need to be supported by dedicated visual analysis tools. A significant example of such a task is the comparison of different connectivity data in the form of weighted graphs. Several approaches have been suggested for graph comparison within information visualization, but the comparison of weighted graphs has not been addressed. We explored the design space of applicable visual representations and present augmented adjacency matrix and node-link visualizations. To assess which representation best support weighted graph comparison tasks, we performed a controlled experiment. Our findings suggest that matrices support these tasks well, outperforming node-link diagrams. These results have significant implications for the design of brain connectivity analysis tools that require weighted graph comparisons. They can also inform the design of visual analysis tools in other domains, e.g. comparison of weighted social networks or biological pathways.

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Basak Alper, Benjamin Bach, Natalie Henry Riche, Tobias Isenberg, and Jean-Daniel Fekete (2013) Weighted Graph Comparison Techniques for Brain Connectivity Analysis. In Stephen Brewster, Susanne Bødker, Patrick Baudisch, and Michel Beaudouin-Lafon, eds., Proceedings of the Annual Conference on Human Factors in Computing Systems (CHI, April 27–May 2, Paris, France). New York. ACM, pages 483–492, 2013. Best Paper Award at ACM CHI 2013.   doi
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BibTeX entry:


@INPROCEEDINGS{Alper:2013:WGC, author = {Basak Alper and Benjamin Bach and Henry Riche, Natalie and Tobias Isenberg and Jean-Daniel Fekete}, title = {Weighted Graph Comparison Techniques for Brain Connectivity Analysis}, booktitle = {Proceedings of the Annual Conference on Human Factors in Computing Systems (CHI, April 27--May 2, Paris, France)}, editor = {Stephen Brewster and Susanne B{\o}dker and Patrick Baudisch and Michel Beaudouin-Lafon}, year = {2013}, pages = {483--492}, publisher = {ACM}, address = {New York}, doi = {10.1145/2470654.2470724}, doi_url = {https://doi.org/10.1145/2470654.2470724}, url = {https://tobias.isenberg.cc/VideosAndDemos/Alper2013WGC}, pdf = {https://tobias.isenberg.cc/personal/papers/Alper_2013_WGC.pdf}, }

This work was done at the AVIZ project group of INRIA, France.